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entity go
that which is perceived or known or inferred to have its own distinct existence (living or nonliving)

physical entity go
an entity that has physical existence

causal agent, cause, causal agency go
any entity that produces an effect or is responsible for events or results

agent go
a substance that exerts some force or effect

drug go
a substance that is used as a medicine or narcotic

brand-name drug, proprietary drug
a drug that has a trade name and is protected by a patent (can be produced and sold only by the company holding the patent)

noun.artifact

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